September is National Cholesterol Education Month, an annual observance aimed at raising awareness about the importance of managing cholesterol levels. The month is dedicated to educating the public about the heart disease risks associated with high cholesterol and the steps individuals can take to help maintain healthy levels.   It’s the perfect time to meet the animated characters called the “Lipid Lurkers”—a visual representation of an often-unnoticed risk lurking in patients’ artery walls. While they may look small and silly, they represent a very real and dangerous health threat. Fat and cholesterol are types of lipids transported through the blood. Certain types of lipids, particularly LDL-C or “bad” cholesterol, can lead to buildup of plaque in the arteries, increasing the risk of heart disease or stroke.   This campaign was created to help educate and empower the nearly 100 million U.S. adults with high LDL-C—especially those who can’t take statins (medications to lower cholesterol) or who have uncontrolled cholesterol and haven’t reached their target levels despite treatment.   Now, there are solutions that offer an alternative to statins— additional options for lowering LDL cholesterol—while also lowering the risk of heart attacks and heart procedures like stent placement or bypass surgery    On Wednesday, September 10, LeAnne Bloedon, MS, RD, Vice President, Clinical Development at Esperion Therapeutics, will be available to discuss the havoc that too much bad cholesterol can cause inside artery walls—and how to lower your cholesterol.   She’ll also outline:   What high LDL cholesterol really does to your body (and why it’s often silent) Why managing cholesterol matters before your first cardiovascular event How the “Lipid Lurkers” campaign is making heart health more accessible, relatable, and even fun Who’s at risk—and what new options are available beyond traditional statins https://www.fiercepharma.com/marketing/esperions-lipid-lurkers-campaign-sheds-light-high-ldl-cholesterol-hiding-artery-walls

#septembercholesterol #cholesterol

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Saccharin, the artificial sweetener used in diet foods like yogurts and sugar-free drinks, can kill multidrug-resistant bacteria—including one of the world’s most dangerous pathogens.

In 2019, antimicrobial resistance (AMR) killed 1.27 million people globally, with resistant infections contributing to nearly 5 million deaths.

Drug-resistant bacteria such as Acinetobacter baumannii, which causes life-threatening infections in people with a weakened immune system, and Pseudomonas aeruginosa, linked to chronic lung infections and sepsis, are on the World Health Organization’s list of top-priority pathogens.

“In exciting work led by our team, we’ve identified a novel antimicrobial—saccharin,” Prof McCarthy said. “Saccharin breaks the walls of bacterial pathogens, causing them to distort and eventually burst, killing the bacteria. Crucially, this damage lets antibiotics slip inside, overwhelming their resistance systems.”

Saccharin has been part of the human diet for longer than 100 years. While it has been extensively tested for safety in people, little was known about its effect on bacteria—until now with a study appearing in EMBO Molecular Medicine.

The international team found that saccharin both stops bacterial growth and disrupts DNA replication and stops the bacteria from forming biofilms—sticky, protective layers that help them survive antibiotics.

They also created a saccharin-loaded hydrogel wound dressing that, in tests, outperformed market-leading silver-based antimicrobial dressings currently used in hospitals.

“This is very exciting,” Prof McCarthy added. “Normally it takes billions of dollars and decades to develop a new antibiotic. But here we have a compound that’s already widely used, and it not only kills drug-resistant bacteria but also makes existing antibiotics more effective.

“Artificial sweeteners are found in many diet and sugar-free foods. We discovered that the same sweeteners you have with your coffee or in a ‘sugar-free’ drink could make some of the world’s most dangerous bacteria easier to treat.”

The World Health Organization has warned that the world is heading toward a “post-antibiotic era,” where common everyday infections could once again become deadly. Overuse of antibiotics in medicine and agriculture has accelerated resistance, and new antibiotics have been slow to arrive.

“This has created a dangerous situation,” said Prof McCarthy. “We urgently need new drugs to treat resistant infections—and saccharin could represent a new therapeutic approach with exciting promise.”

More information: Rubén de Dios et al, Saccharin disrupts bacterial cell envelope stability and interferes with DNA replication dynamics, EMBO Molecular Medicine (2025). DOI: 10.1038/s44321-025-00219-1

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But older Americans should know that there are many practical measures they can take to avoid any falling injuries while still enjoying the physical benefits of being outdoors in summer.

Former dancer Amanda Rees draws on her extensive background in ballet, yoga and tai chi in order to develop a unique personalized, science-based program that can help reduce falls risks. The Bold Program includes customized researched-based exercises designed to improve balance, flexibility, and strength. The program is proven to reduce the incidence of falls by 46% and the exercises can all be done from the comfort of your home.

http://voyagela.com/interview/daily-inspiration-meet-amanda-rees/

#seniorstumbling #preventdangerousinjury #weather #swimming #cdc #adults #physicalbenefits #falling #amandarees #ballet #yoga #taichi #grandma #exercise

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The world is a dangerous place to live; not because of the people who are evil, but because of the people who don’t do anything about it.”

Albert Einstein

#thoughtoftheday, #alberteinstein, #dangerous, #evil, #seesomething, #saysomething,

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Carly Cargill, an energetic young reporter for a major New York Newspaper, tries to find her ground of being as she navigates the perilous streets of the City in the late 1980’s. She is also caught in the maelstrom of the often dangerous choices of the men in her life. The playwright, Eileen Benson, has created a noir throwback reminiscent of vintage films such as “Rebecca,” and “The Philadelphia Story,” with snappy dialogue and well-drawn characters. It won acclaim at its debut performance at the New York New Works Theatre Festival in October.
The Cast:

Carly Cargill ………Danielle Meola Valencia
Kenny Muldoon…………………James Parent
Jeff Paris…………………..William Porterfield
Michael Flannery……. …..Felipe Rodriguez
Jimmie Fitzpatrick…………..Dickson Lane

Written by Eileen Benson
Directed by Dickson Lane

Dickson

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