A new survey revealed that adults and caregivers of children aged 2-17 years living with atopic dermatitis (AD), commonly referred to as eczema, experience sleep disruptions attributed to the condition’s hallmark symptom of itching, which negatively impacts their mood, decreases daytime productivity and heightens stress levels.

AD, one of the most common chronic inflammatory skin diseases, affects over 26 million people in the U.S. alone and up to 10% of adults worldwide. AD occurs most frequently in children, affecting up to 20% worldwide.

The prevalence of atopic dermatitis, an extremely burdensome skin condition that negatively impacts the quality of life of patients suffering from AD and the families and caretakers of patients with AD, continues to grow. Dr. John Browning, a pediatric dermatologist, believes that patients need meaningful solutions that go beyond the surface of the skin. This survey underscores how adults with AD and caregivers of children ages 2-17 years with AD feel about the current treatment landscape and their understanding of concerns related to using topical steroids. It also aimed to explore the extent to which AD symptoms disrupt sleep and, consequently, affect daily functioning for both AD patients and their caregivers.

Key findings from the survey among adult patients with AD (n=502) and caregivers of children 2-17 with AD (n=510):
Itch is a top frustration that impacts patients’ and caregivers’ ability to get quality sleep.

89% of adult patients and caregivers of children aged 2-17 years with atopic dermatitis said itch is a top frustration from atopic dermatitis, and 94% said itching is the top symptom that disrupts sleep.

74% of adult patients and caregivers of children aged 2-17 years with atopic dermatitis stated that atopic dermatitis frequently or occasionally impacts their ability to get quality sleep, and 76% claim they have disrupted sleep an average of one to four nights per week.

These sleep disruptions have negative effects on mood (69%), daily routines (54%), daytime focus (51%), daytime productivity (51%) and stress (50%).

A majority of patients apply topicals before bed to ensure a good night’s sleep, however, patients and caregivers of children with AD have concerns about current treatment options.

72% of adult patients and caregivers of children aged 2-17 years with atopic dermatitis apply topicals before bed in an effort to ensure a good night’s sleep.

46% of caregivers of children aged 2-17 years with atopic dermatitis are extremely or very concerned about using topical steroids for their child’s atopic dermatitis.

Most patients and caregivers feel there should be a wider variety of treatment options.

Current topical treatments present issues that disrupt sleep, such as needing time to dry (58%), causing irritation (51%), and feeling uncomfortable (51%).

83% of adult patients and caregivers of children aged 2-17 years with atopic dermatitis said there is an unmet need in current atopic dermatitis treatment options.

Dr. Browning will discuss how itch (the hallmark symptom of atopic dermatitis), significantly disrupts sleep and the pressing need for new, long-term, treatment options to provide itch relief.

Interview is courtesy: Dermavant Sciences, Inc.
References available on request

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For the millions of people living with psoriasis, like Gloria, the impact on their daily lives extends far beyond the physical symptoms. Among some of the many grievances Gloria can share about her last 10 years living with the condition are:

Strangers commenting on her skin when she’s out in public

Leaving bits of skin on furniture — and even needing to vacuum her bedsheets

Wearing her hair down during the unbearably hot Texas summer to avoid showing affected areas on the back of her neck

Times when people haven’t wanted to touch her skin, such as a cashier not wanting to take a $20 bill from her hands, during a flare-up

Although Gloria tried a number of treatments to help improve her psoriasis, many of these treatments didn’t give her the results she was looking for — as is often the case among psoriasis patients.

Fortunately, there’s hope. A new, innovative treatment in plaque psoriasis is getting high praise from people like Gloria, as well as the medical community. Following more than 25 years of minimal innovation in the topical psoriasis treatment space, the FDA recently approved a steroid-free, prescription cream for plaque psoriasis in adults — the first in its class in the U.S.

Linda Stein-Gold, MD, Director of Dermatology Clinical Research at Henry Ford Health System and Gloria as they discuss the significant impact plaque psoriasis may have on a person’s life and what this new treatment may mean for those who are suffering with plaque psoriasis as well.

Interview is courtesy: Dermavant Sciences

#plaquepsoriasis #psoriasis #advocate #chronicinflammatorydisease #patchesofskin #itchy #painful #disfiguring #gloria #physicalsymptoms #drlindastein-gold #health #clinical #dermavantsciences

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