Saccharin, the artificial sweetener used in diet foods like yogurts and sugar-free drinks, can kill multidrug-resistant bacteria—including one of the world’s most dangerous pathogens.

In 2019, antimicrobial resistance (AMR) killed 1.27 million people globally, with resistant infections contributing to nearly 5 million deaths.

Drug-resistant bacteria such as Acinetobacter baumannii, which causes life-threatening infections in people with a weakened immune system, and Pseudomonas aeruginosa, linked to chronic lung infections and sepsis, are on the World Health Organization’s list of top-priority pathogens.

“In exciting work led by our team, we’ve identified a novel antimicrobial—saccharin,” Prof McCarthy said. “Saccharin breaks the walls of bacterial pathogens, causing them to distort and eventually burst, killing the bacteria. Crucially, this damage lets antibiotics slip inside, overwhelming their resistance systems.”

Saccharin has been part of the human diet for longer than 100 years. While it has been extensively tested for safety in people, little was known about its effect on bacteria—until now with a study appearing in EMBO Molecular Medicine.

The international team found that saccharin both stops bacterial growth and disrupts DNA replication and stops the bacteria from forming biofilms—sticky, protective layers that help them survive antibiotics.

They also created a saccharin-loaded hydrogel wound dressing that, in tests, outperformed market-leading silver-based antimicrobial dressings currently used in hospitals.

“This is very exciting,” Prof McCarthy added. “Normally it takes billions of dollars and decades to develop a new antibiotic. But here we have a compound that’s already widely used, and it not only kills drug-resistant bacteria but also makes existing antibiotics more effective.

“Artificial sweeteners are found in many diet and sugar-free foods. We discovered that the same sweeteners you have with your coffee or in a ‘sugar-free’ drink could make some of the world’s most dangerous bacteria easier to treat.”

The World Health Organization has warned that the world is heading toward a “post-antibiotic era,” where common everyday infections could once again become deadly. Overuse of antibiotics in medicine and agriculture has accelerated resistance, and new antibiotics have been slow to arrive.

“This has created a dangerous situation,” said Prof McCarthy. “We urgently need new drugs to treat resistant infections—and saccharin could represent a new therapeutic approach with exciting promise.”

More information: Rubén de Dios et al, Saccharin disrupts bacterial cell envelope stability and interferes with DNA replication dynamics, EMBO Molecular Medicine (2025). DOI: 10.1038/s44321-025-00219-1

The post Artificial sweetener shows surprising power to overcome antibiotic resistance appeared first on Good News!.

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Non-small cell lung cancer (NSCLC) is the most common form, accounting for approximately 85% of all lung cancers.2 Many people diagnosed with early-stage NSCLC have surgery to remove the cancer; however, for approximately half of these patients, the cancer unfortunately returns.3 Experts agree there is an urgent need for enhanced screening uptake — which has hovered around five percent in recent years amongst those eligible to receive it4 — as well as improved treatment options in early-stage NSCLC to help prevent devastating cancer recurrences.

Studies have shown that treatments beyond chemotherapy, including targeted therapy and now immunotherapy – a type of personalized cancer treatment that activates the immune system to fight cancer – may help improve outcomes for certain patients with early-stage NSCLC after surgery.5 What’s promising is that these studies have now led to U.S. Food and Drug Administration approvals in the post-surgery setting to help reduce the risk of recurrence for patients with specific types of early-stage NSCLC, introducing a new era for these lung cancer patients.

Dr. David Carbone, Professor of Internal Medicine and Director of the James Thoracic Oncology Center at Ohio State University Medical Center will discuss the latest progress, including one of the most recent developments in early-stage lung cancer for patients.

Interview courtesy: Genentech

1 ACS. Key Statistics for Lung Cancer. 2022. Accessed from: https://www.cancer.org/cancer/lung-cancer/about/key-statistics.html.
2 Molina et al. Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship. Mayo Clin Proc. 2008 May; 83(5): 584–594. Accessed September 27, 2021.
3 Yano T, Okamoto T, Fukuyama S, Maehara Y. Therapeutic strategy for postoperative recurrence in patients with non-small cell lung cancer. World J Clin
Oncol. 2014;5(5):1048-1054. doi:10.5306/wjco.v5.i5.1048
4 Fedewa SA, Kazerooni EA, Studts JL, et al. State Variation in Low-Dose CT Scanning for Lung Cancer Screening in the United States. JNCI: The Journal of the National Cancer Institute. doi: 10.1093/jnci/djaa170
5 Zappa et al. Non-small cell lung cancer: current treatment and future advances. Transl Lung Cancer Res. 2016 Jun; 5(3): 288–300. doi:
10.21037/tlcr.2016.06.07.

#davidcarbone #lungcancer #genentech #americancancersociety #factsfigures #disease #aminotherapy #etizolam #go2foundation #nsclc #surgery #chemotherapy #medicine #treatments #patients

The post EXCITING PROGRESS IN DIAGNOSING AND TREATING EARLY-STAGE LUNG CANCER appeared first on Good News!.

Why it’s so critical for the healthcare industry to dedicate energy to SCLC

Advice for those who are beginning their journey with SCLC

Support services that can improve psychosocial health and well-being

Montessa and Abizer will also share details about a new online program called Nothing Small About It, the first-ever digital hub dedicated solely to SCLC patients and their caregivers that aims to provide empathy, education and inspiration through a collection of intimate testimonials from people living with the disease and those who help provide support to them.

It was developed to meet people exactly where they’re at in their individual care journeys, and it is focused exclusively on the psychosocial and educational needs of all people living with this rare form of cancer.

Interview is courtesy: Jazz Pharmaceuticals

1 National Organization for Rare Diseases. Small cell lung cancer. https://rarediseases.org/rarediseases/small-cell-lung-cancer/. Updated 2019. Accessed March 11, 2021.
2 Figg WD, Smith EK, Price DK, et al. Disclosing a diagnosis of cancer: Where and how does it occur? J. Clin. Oncol. 2010 Aug 1;28(22):3630-3635

#lung #cancer #montessa #sclc #abizer #gaslightwala #small #cell #medical #stigma #fear #hopelessness #healthcare #physicians #nurses #scientists #researchers #disease #jazz #pharmaceuticals

The post November is Lung Cancer Awareness Month WORST FEARS SURROUNDING SMALL CELL LUNG CANCER appeared first on Good News!.

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The post GoodNewsLetter: HEALTH/WELLNESS – COVID UV Angel Air Purifiers, Reflexology Classes, Infrared Indoor Saunas, interviews on Hepatitis C, Pain Management, Lung Cancer… appeared first on Good News!.

Despite expanded lung cancer screening guidelines, accelerated progress in the treatment of lung cancer and a continued increase in survival rates, lung cancer remains the leading cause of cancer death in the U.S., 2 Almost one-quarter of all cancer deaths are due to lung cancer – more than breast, prostate and colorectal cancers combined.

Due to the complexities of lung cancer, the adoption of personalized medicine is critical to ensuring people receive the right treatment for their specific type of cancer at the right time. However, many people with the most common type of lung cancer—

non-small cell lung cancer (NSCLC) — are not receiving a fully-informed diagnosis due to a lack of comprehensive biomarker testing that can help identify important characteristics about an individual’s cancer and more precisely inform treatment decisions.

LUNGevity Foundation, the nation’s leading lung cancer-focused non-profit, recently launched No One Missed – a new campaign that aims to increase awareness of comprehensive biomarker testing and empower patients and caregivers to discuss testing with their doctor for a fully-informed diagnosis. Comprehensive Biomarker testing can reveal vital information to help identify the appropriate individualized treatment plan for each NSCLC patient.4

Dr. Jorge Gomez, medical director of the solid tumor oncology unit at Mount Sinai Hospital in New York, and Andrea Ferris, President and CEO of Foundation, as they discuss No One Missed and address:

Recent milestones that will help advance lung cancer care

• Nationwide call for every person diagnosed with NSCLC to receive comprehensive biomarker testing
• Vital information gathered through comprehensive biomarker testing and how it can inform treatment decisions
• 3 key steps for every person living with NSCLC and their caregivers: Talk, Test, Treat
Interview is courtesy: AstraZeneca
[1] US Preventive Services Task Force. Screening for Lung Cancer: US Preventive Services Task Force Recommendation Statement. JAMA. 2021;325(10):962–970. doi:10.1001/jama.2021.1117
2 American Cancer Society. Cancer Facts & Figures 2021. Atlanta: American Cancer Society; 2021
3American Cancer Society. What Is Lung Cancer? Atlanta: American Cancer Society; 2019
4 Gierman HJ, Goldfarb S, Labrador M, et al. Genomic testing and treatment landscape in patients with advanced non-small cell lung cancer (aNSCLC) using real-world data from community oncology practices. J Clin Oncol. 2019;37(suppl; abstr 1585).

#fight #against #lung #cancer #no #one #missed #noonemissed #jorge #gomez #andrea #ferris #longevity #critical #biomarker #testing #foundation #care #astra #zeneca

The post Significant Advancements Achieved in the Fight Against Lung Cancer, We’re Not Done Yet appeared first on Good News!.

NEW RESEARCH FROM PROMINENT CANCER MEETING FOR THOSE WITH LUNG CANCER

People with Lung Cancer, Like Others with Serious Underlying Medical Conditions
Might Be at an Increased Risk for Severe Illness from COVID-19

Lung cancer is the second most common cancer in both men and women. This year, an estimated 228,820 adults (116,300 men and 112,520 women) in the United States will be diagnosed.

The fight against lung cancer continues with new research and scientific advances, including cancer experts investigating potential ways to treat the disease in earlier stages. Some of these latest findings in non-small cell lung cancer (NSCLC), including investigational studies in earlier stages of the disease, were presented at the American Society of Clinical Oncology ASCO20 Virtual Scientific Program.

Roy S. Herbst, MD, PhD of Yale Cancer Center and Smilow Cancer Hospital talks on the latest news from ASCO in the fight against lung cancer.

Lung cancer makes up almost 25% of all cancer deaths. There are two main types of lung cancer: non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). NSCLC is the most common type of lung cancer. In fact, about 80%-85% of lung cancer cases are NSCLC. About 40% of patients are diagnosed at a later stage of disease, such as Stage IV, when the cancer has progressed to other organs. Approximately 10-15% of NSCLC patients in the US and Europe, and 30-40% of patients in Asia have EGFRm NSCLC. The prevalence of EGFR mutations in early stage are estimated to be ~33% in a global NSCLC population.

Interview courtesy: AstraZeneca
#roy #harbst #yale #cancer #center #smilow #covid-19 #covid #19 #covid19 #lung #severe #illness #medical #risk #diagnosed #research #scientific #advances #disease #cell #nsclc #american #society #clinical #oncology #asco #virtual #hospital #astrazeneca

The post NEW RESEARCH FOR LUNG CANCER appeared first on Good News!.

The post Dr. Ronald Minutoli – Discusses INDOOR ALLERGIES, important anytime of the year, pay attention and make changes to improve your health. appeared first on Good News!.

Subject: 60 sec PSAs-Features about Pneumonia Vaccine for 50+ and Older Adults
Age is a state of mind, except when it comes to your immune system. On behalf of Pfizer, an official with the American Lung Association, a former U.S. surgeon general, and golf professional Jim Furyk discuss how older adults should find out if they need to be vaccinated against “pneumococcal pneumonia”.

August is National Immunization Awareness Month, yet the features are evergreen.

Click these links to listen and download audio for use in your news, feature or PSA programming. Scripts are below.

:60 Feature – Dr. Norm Edelman, American Lung Association
http://radiospace.com/pfizer.htm

:60 Feature – Dr. Regina Benjamin, former U.S. Surgeon General
(African American version)
http://radiospace.com/pfizer2.htm

:60 Feature – Jim Furyk, golf professional
http://radiospace.com/pfizer3.htm – Click on link to listen to them!

(In addition, Below is the SCRIPT if you would like to read it yourself for news!)

Let us know if and how you’re able to use these.

:60 Script for Dr. Edelman, American Lung Association
Age is a state-of-mind—except when it comes to your immune-system: Adults as young as 50 are at increased risk for serious infectious-diseases—like “pneumococcal pneumonia”—because of their aging immune-systems. A recent “Harris Poll”—conducted for the “American Lung Association” and “Pfizer”, of one-thousand U-S adults—found 85-percent of adults age-50 to -75 believe people their age are at risk for “pneumococcal pneumonia”. But, only half believe they’re personally at risk. Doctor Norm Edelman—senior scientific-advisor to the “Lung Association”…

“It’s estimated that a quarter-of-a-million Americans, over 50, are hospitalized, each year, with ‘pneumococcal pneumonia’—with an average hospital-stay of five days. Even otherwise-healthy and -active older-adults need to be aware of their increased risk—because of their aging immune-systems.”

If you’re 50 or older, talk to your doctor about your personal risk for “pneumococcal pneumonia”—and see if you’re up-to-date on your vaccinations. Learn more at “who-pneu”-dot-com; that’s “w-h-o-p-n-e-u”-dot-com. Brought to you by the “American Lung Association”, in partnership with “Pfizer”.

:60 Script for Dr. Regina Benjamin, former U.S. Surgeon General
Adults age-65-plus are at increased risk for vaccine-preventable diseases—like “pneumococcal pneumonia”—because our immune-systems weaken, as we age. Worse still, vaccination-rates among African-American adults are lagging—leaving them at greater risk for vaccine-preventable diseases, like flu, shingles, or “pneumococcal pneumonia”. Former Surgeon-General, Doctor Regina Benjamin, explains…

“African-Americans are more likely to suffer from certain chronic health-conditions—leaving us at increased risk for certain vaccine-preventable diseases. Despite this, far-fewer older African-Americans than their White counterparts report receiving preventive health-services—such as vaccinations. I urge all African-American adults age-65-plus to know their risks—and [to] think prevention: Maintain a healthy diet and lifestyle, wash your hands frequently, and talk to your doctor—to ensure that you’re up-to-date on all your vaccinations.”

This message was brought to you by “Pfizer”.

:60 Script for Jim Furyk, golf professional
Golf-professional, Jim Furyk [“fyur-ick”], has had his coach and father, Mike, by his side—throughout his impressive career. But, now that Mike’s getting older, Jim is encouraging him to be more proactive—when it comes to his health…

“I wouldn’t be near the golfer—or man—[that] I am today without my dad. And now, it’s time for me to coach him, about taking personal responsibility for his health. Just like overcoming the hazards along a golf-course, understanding your risk for potentially serious infectious-diseases—like ‘pneumococcal pneumonia’—can help you stay on-course.”

“Pneumococcal pneumonia” is a potentially serious and life-threatening illness. Even healthy adults over 65 are at increased risk—because our immune-system naturally weakens with age…

“Vaccines aren’t just for kids: As you and your parents age, consider the importance of adult-vaccination. And, if you’re 65 or older, speak with a doctor or pharmacist—to make sure [that] you’re up-to-date, on ‘C-D-C’-recommended vaccines.”

For more, visit “know-pneumonia”-dot-com; that’s “k-n-o-w-pneumonia”-dot-com. Sponsored by “Pfizer”.

The post “AUGUST IS “NATIONAL IMMUNIZATION AWARENESS MONTH”! appeared first on Good News!.

If you were given a diagnosis of lung cancer and told you had six months to live – that’s pretty much a death sentence, right? Wrong! When Dr. Carl Helvie was given that very diagnosis 38 years ago he decided his last months would be without the debilitating effects of traditional medicine. Now, at age 80, he is not only free of chronic illnesses and prescribed medications but is the longest living lung cancer survivor! His new book, You Can Beat Lung Cancer: Using Alternative/Integrative Interventions (Ayni Books), is one of the most comprehensive books on alternative treatment for lung cancer available today.

We have been conditioned to believe that surgery, chemotherapy and radiation are the only way to fight cancer but, according to Helvie, “this could not be more wrong!” Interestingly, a team of researchers in Washington state recently discovered by ‘accident’ that chemotherapy does not treat or cure cancer at all but rather fuels the growth of cancer cells, making it even more difficult to destroy the second time around.

Using holistic natural interventions of supplements, herbs, enzymes, diet, prayer, meditation, visualization and more, Dr. Helvie not only overcame his cancer but prevented a recurrence. So, considering only 11% of Americans over age 65 are free of chronic illnesses, and by age 75 the average is three chronic illnesses and five prescribed medications, following the steps outlined in his book is like being given back 20+ years of life!

Dr. Helvie’s book is based on his 60-year background in medicine and research, and input from some of the leading medical and health practitioners currently in the field today. By shedding light on the alternatives to traditional harsh treatments, he is arming us with the necessary information to make a rational decision should we ever be faced with this diagnosis.

Dr. Carl Helvie is a registered nurse with two masters and a doctorate in public health and wellness. He has 60 years experience as a nurse practitioner, educator, author and researcher and is the recipient of numerous awards and has listings in Who’s Who In American Nursing, Men of Achievement, American Men and Women of Science, just to name a few. He has eight published books, has contributed to others, and has published or presented internationally over 100 papers and articles. He developed and published a nursing theory that is used worldwide and has established a nursing center that provides primary care for homeless and low-income individuals and families.

Dr. Helvie currently writes for a magazine and is the host of a radio show on natural holistic health. For more information, please visit: www.BeatLungCancer.net.

Available at fine bookstores or online outlets
You Can Beat Lung Cancer: Using Alternative/Integrative Interventions
By Dr. Carl O. Helvie
Publisher: Ayni Books
Released: November 16, 2012
ISBN-10: 1780992831
ISBN-13: 978-1780992839

###

Reviews:

G. Edward Griffin, Author of World Without Cancer, The Politics of Cancer Therapy, President of American Media: “… one of the most comprehensive books available on alternative treatments for lung cancer…explains the treatments used successfully by [this] cancer survivor /health professional and some of the leading medical and health practitioners in the field.”

Julian Kenyon, MD, Medical Director, The Dove Clinic for Integrated Medicine: “Helvie’s case is remarkable…a man of great courage, who has followed a natural approach to his life-threatening illness and this has resulted in a cure…”

Patrick Quillin, PhD, RD, CNS; Author of Beating Cancer with Nutrition and Adjuvant Nutrition in Cancer Treatment: “Lung cancer is both common and lethal…Helvie approaches subject as both health care professional and lung cancer survivor…invaluable advice for beating this disease that is often called “a death sentence” if diagnosed in later stages of the disease…not only offered his invaluable experiences as a cancer victor, but adds the wisdom of other world class experts on the subject of cancer treatment. If you or a loved one have lung cancer, then this book could become your ‘get out of jail free’ card toward recovery or at least a dramatic extension in quality and quantity of life.”

Frank Shallenberger, MD, HMD, ABAAM, Author, Medical Director, The Nevada Center of Alternative Medicine: “If you are ever diagnosed with advanced cancer, the odds are very good that your oncologist will tell you that unless you immediately consent to chemotherapy you are going to die. This is a lie! I know, I’ve been treating conventional chemotherapy failures for years. Other than for leukemia or lymphoma, conventional chemotherapy is almost always a death sentence. There are so many more effective ways to treat advanced cancer, and Dr. Carl Helvie’s [book] describes some of the most effective.”

The post Dr. Carl Helvie appeared first on Good News!.