step Archives - Good News!

Thought for the Day…08/05/25

Austin Tang — Tue, 05 Aug 2025 13:57:22 +0000

My friend, Judy Gilbert, the hockey legends wife & Humanitarian is Buzz Aldrin friend…she wrote on Facebook

Buzz Aldrin. Made it

To the moon…and back. He told me it took so much more than education, discipline and physical strength. It took years of determination and believing that any goal is possible “but it was still hard to believe when l took my first step onto the moon’s surface.”

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GoodNewsLetter/YouTube 06/13/25: FREEDOM & PEACE, Health and Wellness Content, Myasthenia…

Austin Tang — Fri, 13 Jun 2025 18:29:12 +0000

Here is the link: https://youtu.be/AnilAC0TSF0

What is FREEDOM for you? What is PEACE for you?

Why do I ask this question? It is because for me these two “Ways of Living Life” represent happiness, fulfillment, care for ALL.

Let’s be messengers for FREEDOM & PEACE, so as our “Thought for Day states”

” Success begins with the first step you take each morning.

Don’t just wake up — get up and conquer the day.”

Have a great day. Stay blessed always.

Once again, please put a hold on your calendar for September 19, 20, 21 for our International Day of Peace & NYC Climate Weekend Events here in NYC and around the world.

Here is a Draft of a Press Release that we will be sending out soon.

UN International Day of Peace 2025, September 21, Expands to a Global Weekend for a World Cease Fire, Unity, Music, and Climate Action. New York City Leads the Call.

THE INTERNATIONAL DAY OF PEACE REQUESTS WORLDWIDE CEASEFIRE (IN THE KILLING FIELDS, STREETS, SCHOOLS, HOMES…EVERYWHERE) CONDUCT ACTS OF PEACE, HUMAN PEACE CIRCLES, YOUR IMAGINATION – WE NEED YOU TO HELP US MAKE THIS HAPPEN…

JOIN US. WE ARE GATHERING CONCERNED CITIZENS who want to help Pause the World on September 21, 2025, at 12 noon. www.pausetheworldforpeace.org McKinsey states 2 billion are aware of the day, and we want all 193 countries of the UN, who created the day unanimously, and Everyone Else to honor the day. If you want to help us MAKE THIS HAPPEN, PLEASE email me: Paul.sladkus1@gmail.com or call 212 647 1212. Our first Zoom meeting will be Tuesday, June 17th at 3 pm EST.

Here is the link, and please rsvp to Paul.Sladkus1@gmail.com

https://us04web.zoom.us/j/2459904503?pwd=ZERZU2p5dU1NZmtaeFpTZXNxNi9rUT09

Meeting ID: 245 990 4503. Passcode: 9pjTYt

Please share our newsletters with your community, as we are growing and our content can help save lives.

Here is HEALTH AND WELLNESS GOOD NEWS CONTENT…OUR 27TH ANNIVERSARY OF OUR WEBSITE AND YOUTUBE SITE WILL BE JULY 4TH. THANKS TO YOU ALL, WE ARE STILL IN THE GOOD NEWS BUSINESS.

LEARN MORE ABOUT

GENERALIZED MYASTHENIA

GRAVIS (gMG)

Please donate here and possibly win a trip to the Montauk Manor: https://goodnewsplanet.com/pausetheworld/peace-day-donations/

IT’S NOT TOO LATE TO BE INVOLVED BY SPONSORING, DONATING (NOTE: IF YOU BRING US A SPONSOR/DONOR YOU RECEIVE 20% AS A NEW BUSINESS CONSULTANT) PLEASE CONSIDER VOLUNTEERING FOR THE INTERNATIONAL DAY OF PEACE WEEKEND EVENTS AND CONCERT IN TIMES SQUARE ON SEPTEMBER 19, 20, 21, 2025… CALL 212 647 1212 or email me paul.sladkus1@gmail.com

2025-2026

Peace & Earth Day

Marketing Proposal

Lastly, if you care about your money, please tune in to WOR 710 Radio on Sunday at 10:30 AM. Here you can listen and call in to Legal Expert and Elder Care Lawyer, 14 Year NYS Representative and Dr. Phil, ET, Good Morning America…Guest Lawyer, Ann-Margaret Carrozza, ESQ.

Ann is BRILLIANT, AND YOUR MONEY IS BRILLIANT, AND YOU ARE BRILLIANT IF YOU ARE SMART ENOUGH TO PROTECT IT.

Paul Sladkus is Ann’s Co-Host. Email me paul.sladkus1@gmail.com if you want me to ask her a question, or just call in (800-321-0710) and listen; it might be one of the most important programs in you and your family’s life.

Ann-Margaret Carrozza,

Asset Protection Lawyer,

STAY WELL

Please support our nonprofit, 501 C 3, Good News Corporation at http://goodnewsplanet.com/peacedayparty/peace-day-donations/

LET’S GROW TOGETHER. GOOD NEWS MOTTO: “All we are is what we are with each other.” Zeal

With Respect. Love and May Peace Prevail on Earth, For Information Contact:

Reverend Paul Sladkus, All Faiths and Spiritual,

Founder, Good News Corporation 501 C 3 212 647 1212 paul.sladkus1@gmail.com and our Good News and Peace Worldwide Team who make our Peace Day 9/21 happen.

www.pausetheworldforpeace.org,www.goodnewsplanet.TV, www.youtube.com/goodnewsbroadcast

Social Networks: www.Facebook.com/PaulSladkus, LinkedIn Paul Sladkus, Twitter/X Good News to Go, Instagram PausetheWorld

LET’S GROW TOGETHER. GOOD NEWS MOTTO: ALL WE ARE IS WHAT WE ARE WITH EACH OTHER. ZEAL

For more information contact:

Reverend Paul Sladkus, All Faiths and Spiritual 212 647 1212

New York, NY, Montauk, NY

PS – SPECIAL OPPORTUNITY FOR OUR FRIENDS AND MEMBERS: Looking for a vacation rental, SHORT TERM, in Montauk, this year and or entire summer in 2026, here is our listing https://pausetheworldforpeace.org/2025/04/16/36000-2br-one-of-a-kind-summer-rental-opportunty-historic-montauk-manor-montauk/ call me. Paul 917 687 1790

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Thought for the Day…06/09/25

Austin Tang — Mon, 09 Jun 2025 14:29:02 +0000

Good morning friends.

” Success begins with the first step you take each morning.

Don’t just wake up — get up and conquer the day.”

Have a great day. Stay blessed always.

The post Thought for the Day…06/09/25 appeared first on Good News!.

Thought for the Day…08/26/24

Austin Tang — Mon, 26 Aug 2024 13:15:20 +0000

ACCEPT that you will never be perfect, life will always have challenges, and other people will disappoint you sometimes.

Acceptance is the first step towards peace.

Good morning

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How to Map a Fly Brain in 20 Million Easy Steps

Austin Tang — Thu, 28 Oct 2021 16:20:59 +0000

By Emily Anthes

Published Oct. 26, 2021Updated Oct. 27, 2021

The brain of a fruit fly is the size of a poppy seed and about as easy to overlook.

“Most people, I think, don’t even think of the fly as having a brain,” said Vivek Jayaraman, a neuroscientist at the Janelia Research Campus of the Howard Hughes Medical Institute in Virginia. “But, of course, flies lead quite rich lives.”

Flies are capable of sophisticated behaviors, including navigating diverse landscapes, tussling with rivals and serenading potential mates. And their speck-size brains are tremendously complex, containing some 100,000 neurons andtens of millions of connections, or synapses, between them.

Since 2014, a team of scientists at Janelia, in collaboration with researchers at Google, have been mapping these neurons and synapses in an effort to create a comprehensive wiring diagram, also known as a connectome, of the fruit fly brain.

The work, which is continuing, is time-consuming and expensive, even with the help of state-of-the-art machine-learning algorithms. But the data they have released so far is stunning in its detail, composing an atlas of tens of thousands of gnarled neurons in many crucial areas of the fly brain.

And now, in an enormous new paper, being published on Tuesday in the journal eLife, neuroscientists are beginning to show what they can do with it.

By analyzing the connectome of just a small part of the fly brain — the central complex, which plays an important role in navigation — Dr. Jayaraman and his colleagues identified dozens of new neuron types and pinpointed neural circuits that appear to help flies make their way through the world. The work could ultimately help provide insight into how all kinds of animal brains, including our own, process a flood of sensory information and translate it into appropriate action.

It is also a proof of principle for the young field of modern connectomics, which was built on the promise that constructing detailed diagrams of the brain’s wiring would pay scientific dividends.

“It’s really extraordinary,” Dr. Clay Reid, a senior investigator at the Allen Institute for Brain Science in Seattle, said of the new paper. “I think anyone who looks at it will say connectomics is a tool that we need in neuroscience — full stop.”

Credit…Matt Staley, Janelia Research Campus

‘Your fly brain is cooked’

The only complete connectome in the animal kingdom belongs to the humble roundworm, C. elegans. The pioneering biologist Sydney Brenner, who would later go on to win a Nobel Prize, started the project in the 1960s. His small team spent years on it, using colored pens to trace all 302 neurons by hand.

“Brenner realized that to understand the nervous system you had to know its structure,” said Scott Emmons, a neuroscientist and geneticist at Albert Einstein College of Medicine, who later used digital techniques to create new C. elegans connectomes. “And that’s true across biology. Structure is so important.”

Brenner and his colleagues published their landmark paper, which clocked in at 340 pages, in 1986.

But the field of modern connectomics did not take off until the 2000s, when advances in imaging and computing finally made it feasible to map the connections in larger brains. In recent years, research teams around the world have started assembling connectomes of zebrafish, songbirds, mice, humans and more.

When the Janelia Research Campus opened in 2006, Gerald Rubin, its founding director, set his sights on the fruit fly. “I don’t want to offend any of my worm colleagues, but I think flies are the simplest brain that actually does interesting, complex behavior,” Dr. Rubin said.

Several different teams at Janelia have embarked on fly connectome projects in the years since, but the work that led to the new paper began in 2014, with the brain of a single, five-day-old female fruit fly.

Researchers cut the fly brain into slabs and then used a technique known as focused-ion beam scanning electron microscopy to image them, layer by painstaking layer. The microscope essentially functioned like a very tiny, very precise nail file, filing away an exceedingly thin layer of the brain, snapping a picture of the exposed tissue and then repeating the process until nothing remained.

“You’re simultaneously imaging and cutting off little slices of the fly brain, so they don’t exist after you’re done,” Dr. Jayaraman said. “So if you screw something up, you’re done. Your goose is cooked — or your fly brain is cooked.”

The team then used computer vision software to stitch the millions of resulting images back together into a single, three-dimensional volume and sent it off to Google. There, researchers used advanced machine-learning algorithms to identify each individual neuron and trace its twisting branches.

Finally, the Janelia team used additional computational tools to pinpoint the synapses, and human researchers proofread the computers’ work, correcting errors and refining the wiring diagrams.

Last year, the researchers published the connectome for what they called the “hemibrain,” a large portion of the central fly brain, which includes regions and structures that are crucial for sleep, learning and navigation.

The connectome, which is accessible free online, includes about 25,000 neurons and 20 million synapses, far more than the C. elegans connectome.

“It’s a dramatic scaling up,” said Cori Bargmann, a neuroscientist at the Rockefeller University in New York. “This is a tremendous step toward the goal of working out the connectivity of the brain.”

Welcome to orientation

Credit…FlyEM/Janelia Research Campus

Once the hemibrain connectome was ready, Dr. Jayaraman, an expert on the neuroscience of fly navigation, was eager to dive into the data on the central complex.

The brain region, which contains nearly 3,000 neurons and is present in all insects, helps flies build an internal model of their spatial relationship to the world and then select and execute behaviors appropriate for their circumstances, such as searching for food when they are hungry.

“You’re telling me you can give me the wiring diagram for something like this?” Dr. Jayaraman said. “This is better industrial espionage than you could get by getting insights into the Apple iPhone.”

He and his colleagues pored over the connectome data, studying how the region’s neural circuits were put together.

For instance, Hannah Haberkern, a postdoctoral associate in Dr. Jayaraman’s lab, analyzed the neurons that send sensory information to the ellipsoid body, a doughnut-shape structure that acts as the fly’s internal compass.

Dr. Haberkern found that neurons that are known to transmit information about the polarization of light — a global environmental cue that many animals use for navigation — made more connections to the compass neurons than did neurons that transmit information about other visual features and landmarks.

The neurons dedicated to polarization of light also connect to — and are capable of strongly inhibiting — brain cells that provide information about other navigational cues.

The researchers hypothesize that fly brains may be wired to prioritize information about the global environment when they are navigating — but also that these circuits are flexible, so that when such information is inadequate, they can pay more attention to local features of the landscape. “They have all these fallback strategies,” Dr. Haberkern said.

Fruit fly phone home

Other members of the research team identified specific neural pathways that seem well suited to helping the fly keep track of its head and body orientation, anticipate its future orientation and traveling direction, calculate its current orientation relative to another desired location and then move in that direction.

Imagine, for instance, that a hungry fly temporarily abandons a rotting banana to see whether it can rustle up something better. But after a (literally) fruitless few minutes of exploration, it wants to return to its previous meal.

The connectome data suggests that certain brain cells, technically known as PFL3 neurons, help the fly pull off this maneuver. These neurons receive two critical inputs: They get signals from neurons that track the direction the fly is facing as well as from neurons that may be keeping tabs on the direction of the banana.

After receiving those signals, the PFL3 neurons then send out their own message to a set of turning neurons that prompt the fly to veer off in the correct direction. Dinner is served, again.

“Being able to trace that activity through that circuit — from sensory back to motor through this complex intermediate circuit — is really amazing,” said Brad Hulse, a research scientist in Dr. Jayaraman’s lab who led this part of the analysis. The connectome, he added, “showed us a lot more than we thought it was going to.”

And the group’s paper — a draft of which includes 75 figures and stretches to 360 pages — is just the beginning.

“It just really provides this ground truth for exploring this brain region further,” said Stanley Heinze, an expert on insect neuroscience at Lund University in Sweden. “It’s just enormously impressive.”

And just plain enormous. “I wouldn’t really treat it as a paper but more as a book,” Dr. Heinze said.

In fact, the paper is so large that the preprint server bioRxiv initially declined to publish it, perhaps because the administrators — understandably — thought it actually was a book, Dr. Jayaraman said. (The server ultimately did post the study, after a few extra days of processing, he noted.)

The paper’s publication in the journal eLife “required some special permissions and back-and-forth with editorial staff,” Dr. Jayaraman added.

Fly-ing lessons

There are limitations to what a snapshot of a single brain at a single moment in time can reveal, and connectomes do not capture everything of interest in an animal brain. (Janelia’s hemibrain connectome omits glial cells, for instance, which perform all sorts of important tasks in the brain.)

Dr. Jayaraman and his colleagues stressed that they would not have been able to infer so much from the connectome if not for decades of prior research, by many other scientists, into fruit fly behavior and basic neuron physiology and function, as well as theoretical neuroscience work.

But the wiring diagrams can help researchers investigate existing theories and generate better hypotheses, figuring out what questions to ask and which experiments to conduct.

Credit…Peter Yeeles/Alamy

“Now what we’re really excited about is taking those ideas that the connectome inspired and going back to the microscope, going back to our electrodes and actually recording the brain and seeing if those ideas are true,” Dr. Hulse said.

Of course, one could — and some have — asked why a fruit fly’s brain circuitry matters.

“I get asked this at the holidays a lot,” Dr. Hulse said.

Flies are not mice or chimps or humans, but their brains perform some of the same basic tasks. Understanding the basic neural circuitry in an insect could provide important clues to how other animal brains approach similar problems, said David Van Essen, a neuroscientist at Washington University in St. Louis.

Gaining a deep understanding of the fly’s brain “also gives us insights that are very relevant to the understanding of mammalian, and even human, brains and behavior,” he said.

Creating connectomes of larger, more complex brains will be enormously challenging. The mouse brain contains roughly 70 million neurons, the human brain a whopping 86 billion.

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Watch this awesome jugalbandi BB between Spanish step dancer & Indian Kathak dancer. It’s sheer Magic when violin starts.

Austin Tang — Wed, 25 Aug 2021 19:49:05 +0000

The post Watch this awesome jugalbandi BB between Spanish step dancer & Indian Kathak dancer. It’s sheer Magic when violin starts. appeared first on Good News!.

Thought of the Day

Austin Tang — Wed, 07 Apr 2021 16:53:14 +0000

Thought!!!

Life is a game of chess. You cannot undo the moves, but you can make the nest step better.

Good Morning!!!
Have a successful day.

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Thought for the Day…

admin — Fri, 20 Oct 2017 17:00:01 +0000

“Which Step Have You Reached Today? I Won’t Do It, I Can’t Do It, I Want To Do It, How Do I Do It, I’ll Try To Do It, I Can To It, I Will Do It, Yes!!I Did It!!” – Daily Post

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No Gun Violence in Brooklyn and Everywhere!!

admin — Fri, 07 Aug 2015 16:32:15 +0000

We can have Peace – Gun Violence Being Discussed in front of an Open Casket with pictures of victims inside of it. .

Borough President Eric Adams and Community Leaders unite over Gun Violence. In front of a casket, BP Adams and community leaders speak about controlling and ending Gun Violence in Brooklyn and everywhere. BP discuss a Five Step Approach. The casket will be on display for 5 days in front of Borough Hall in Brooklyn.

There are real solutions that were brought up, real people doing them, so everyone, everywhere pay attention and share this Anti- Violence message. Join our www.peacedayparty.org as well, as millions will be involved with the International Day of Peace.

Paul and the Good News Team.

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